Isopropylsulphamoyl chloride → HCID 54045509, compound

HRID 1459006Notes

Reaction equation

Cl.[C:2]([C:4]1[CH:29]=[CH:28][C:7]([CH2:8][NH:9][C:10](=[O:27])[C@@H:11]2[CH2:15][CH2:14][CH2:13][N:12]2[C:16](=[O:26])[C@@H:17]([CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[NH2:18])=[CH:6][CH:5]=1)#[N:3].[CH:30]([NH:33][S:34](Cl)(=[O:36])=[O:35])([CH3:32])[CH3:31]>>[C:2]([C:4]1[CH:5]=[CH:6][C:7]([CH2:8][NH:9][C:10](=[O:27])[C@@H:11]2[CH2:15][CH2:14][CH2:13][N:12]2[C:16](=[O:26])[C@@H:17]([CH2:19][C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)[NH:18][S:34]([NH:33][CH:30]([CH3:32])[CH3:31])(=[O:36])=[O:35])=[CH:28][CH:29]=1)#[N:3]

Participants

Reactant 2

HCID 117737Isopropylsulphamoyl chloride

HCID 70066102HCID 70066102, compound

Product 1

HCID 54045509HCID 54045509, compound

Procedure

D-Phenylalanylproline (p-cyanobenzyl)amide hydrochloride was reacted with isopropylaminosulfonyl chloride as in Example 1c.

Sources & evidence

ORD record: ord-438d61a9bbb842758b9a32b1e1d87404
Source dataset: uspto-grants-1998_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05852051

Reaction notes

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