2-Naphthalenecarboxaldehyde → HCID 22876505, compound

Participants

Reaction Steps

Using 1.00 g (7.29 mmol) of (R)-phenylglycinol ((R)-VIII-2) and β-naphthoaldehyde, a similar operation was carried out to obtain (R)-N-(β-naphthyl)methyl-2-phenylglycinol (2.01 g) ((R)-II-3) quantitatively. ##STR317## [α] D20 ÷3.1° (C=0.1, CH 3OH) 1 H-NMR (CDCl3) δ ppm: 7.30-7.80 (12 H, m, aromatic-H), 3.50-4.30 (5 H, m, other-H), 2.30 (1 H, br, OH), 2.02 (1 H, br s, NH)

Provenance & Evidence