2-Amino-4,6-dimethylpyridine → HCID 178475872, compound

HRID 1459178Notes

Reaction equation

HRID 1459178 reaction equation
[C:1]([OH:4])(=[O:3])[CH3:2].N=C1C(C)CCCN1.[NH2:13][C:14]1[CH:19]=[C:18]([CH3:20])[CH:17]=[C:16]([CH3:21])[N:15]=1>>[C:1]([OH:4])(=[O:3])[CH3:2].[NH:13]=[C:14]1[CH2:19][CH:18]([CH3:20])[CH2:17][CH:16]([CH3:21])[NH:15]1

Participants

3

Reactant 2

HCID 215072-Amino-4,6-dimethylpyridineHCID 178475853HCID 178475853, compound

Product 1

HCID 178475872HCID 178475872, compound

Procedure

The method of preparation of 2-Imino-3-methylpiperidine acetate, EXAMPLE 6, was used to convert 2-amino-4,6-dimethylpyridine to the title compound which was obtained as a white solid. The analysis of the product was found to be consistent with the proposed structure. m.p. 163°-166° C. MH+=127; 1H NMR (D2O): δ3.48-3.40 (m, 1H); 2.52-2.40 (m, 1H); 2.07-1.95 (m, 1H); 1.85-1.75 (m, 2H); 1.75 (s, 3H); 1.12 (d, J=6.3 Hz, 3H); 1.02-0.92 (m, 1H); 0.86 (d, J=6.3 Hz, 3H).

Sources & evidence

ORD record
ord-977fae680111499a8f6417f745cc157c
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

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