Ammonium Chloride → HCID 178425009, compound

HRID 1459184Notes

Reaction equation

HRID 1459184 reaction equation
CO[C:3]1[CH:4]([CH3:11])[CH2:5][CH2:6][CH2:7][CH:8]([CH3:10])[N:9]=1.[Cl-:12].[NH4+:13]>CO.C(Cl)Cl>[ClH:12].[CH3:11][CH:4]1[CH2:5][CH2:6][CH2:7][CH:8]([CH3:10])[NH:9][C:3]1=[NH:13]

Participants

5

Reactant 2

HCID 25517Ammonium ChlorideHCID 15453857HCID 15453857, compound

Product 1

HCID 178425009HCID 178425009, compoundYield 104.1%

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6344DichloromethaneSolvent

Procedure

The product of EXAMPLE 40 (380 mg, 2.4 mmol) in 15 mL of MeOH and 5 mL of CH2Cl2 was reacted with ammonium chloride (104 mg, 2.0 mmol) by the method of EXAMPLE 27 to yield 368 mg (100%) of the title material.

Sources & evidence

ORD record
ord-d29061809aa649e6b0431374be50c2a4
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

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