Ammonium Chloride → HCID 178425251, compound

HRID 1459186Notes

Reaction equation

HRID 1459186 reaction equation
CO[C:3]1[CH2:4][CH2:5][CH2:6][CH2:7][CH:8]([CH3:10])[N:9]=1.[Cl-:11].[NH4+:12]>CO>[ClH:11].[CH3:10][CH:8]1[NH:9][C:3](=[NH:12])[CH2:4][CH2:5][CH2:6][CH2:7]1

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 12348061HCID 12348061, compound

Product 1

HCID 178425251HCID 178425251, compoundYield 74.8%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of EXAMPLE 45 (125 mg, 0.89 mmol) in 9.0 mL of MeOH was reacted with ammonium chloride (44.0 mg, 0.83 mmol) by the method of EXAMPLE 27 to yield 101 mg (63%) of the title material.

Sources & evidence

ORD record
ord-8dfccc6ef9c74f3d9c2c0daa1ddcd447
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

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