Ammonium Chloride → HCID 178479077, compound

HRID 1459187Notes

Reaction equation

HRID 1459187 reaction equation
CO[C:3]1[CH2:4][CH2:5][CH2:6][CH:7]([C:10]([F:13])([F:12])[F:11])[CH2:8][N:9]=1.[Cl-:14].[NH4+:15]>CO>[ClH:14].[F:11][C:10]([F:13])([F:12])[CH:7]1[CH2:8][NH:9][C:3](=[NH:15])[CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 18428544HCID 18428544, compound

Product 1

HCID 178479077HCID 178479077, compoundYield 98.2%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of EXAMPLE 52 (77 mg, 0.39 mmol) in 3.0 mL of MeOH was reacted with ammonium chloride (21.0 mg, 0.39 mmol) by the method of EXAMPLE 27 to yield 83 mg (94%) of the title material.

Sources & evidence

ORD record
ord-4f8957a6518a40078bc52bb6a5af6c56
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

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