Ammonium Chloride → HCID 178436301, compound

HRID 1459188Notes

Reaction equation

HRID 1459188 reaction equation
[CH2:1]([CH:3]1[CH2:9][CH2:8][CH2:7][CH2:6][C:5](OC)=[N:4]1)[CH3:2].[Cl-:12].[NH4+:13]>CO>[ClH:12].[CH2:1]([CH:3]1[NH:4][C:5](=[NH:13])[CH2:6][CH2:7][CH2:8][CH2:9]1)[CH3:2]

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 18428596HCID 18428596, compound

Product 1

HCID 178436301HCID 178436301, compoundYield 84.5%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of EXAMPLE 57 (802 mg, 5.2 mmol) in 15 mL of MeOH was reacted, with ammonium chloride (225 mg, 4.2 mmol) by the method of EXAMPLE 27 to yield 627 mg (82%) of the title material.

Sources & evidence

ORD record
ord-8e67136e58b449afa7658294f4f6d2e7
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

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