Ammonium Chloride → HCID 178479040, compound

HRID 1459197Notes

Reaction equation

HRID 1459197 reaction equation
[CH:1]1([CH:7]2[CH2:13][CH2:12][CH2:11][CH2:10][C:9](OC)=[N:8]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl-:16].[NH4+:17]>CO>[ClH:16].[CH:1]1([CH:7]2[NH:8][C:9](=[NH:17])[CH2:10][CH2:11][CH2:12][CH2:13]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 18428625HCID 18428625, compound

Product 1

HCID 178479040HCID 178479040, compoundYield 75.8%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of EXAMPLE 94 (730 mg, 3.45 mmol) in 30 mL of MeOH was reacted with ammonium chloride (177 mg, 3.31 mmol) by the method of EXAMPLE 27 to yield 579 mg (75%) of the title material.

Sources & evidence

ORD record
ord-3f7c01f880594173b2ef7418dbc8262b
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

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