Ammonium Chloride → HCID 178447989, compound

HRID 1459210Notes

Reaction equation

HRID 1459210 reaction equation
CO[C:3]1[CH2:4][C@H:5]([CH3:13])[CH2:6][CH2:7][C@@H:8]([CH:10]([CH3:12])[CH3:11])[N:9]=1.[Cl-:14].[NH4+:15]>CO>[ClH:14].[CH3:11][CH:10]([C@H:8]1[NH:9][C:3](=[NH:15])[CH2:4][C@H:5]([CH3:13])[CH2:6][CH2:7]1)[CH3:12]

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 54145544HCID 54145544, compound

Product 1

HCID 178447989HCID 178447989, compoundYield 73.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of EXAMPLE 135 (690 mg, 3.8 mmol) in 20 mL of MeOH was reacted with ammonium chloride (201 mg, 3.8 mmol) by the method of EXAMPLE 27 to yield 570 mg (73%) of the white solid title material.

Sources & evidence

ORD record
ord-3b1d08e4c879416989bae2fe4e5c1bc6
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

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