1,3,4,5-Tetrahydro-2H-1-benzazepin-2-one → HCID 18428530, compound

HRID 1459219Notes

Reaction equation

HRID 1459219 reaction equation
[NH:1]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[CH2:5][CH2:4][CH2:3][C:2]1=[O:12].F[B-](F)(F)F.[CH3:18][O+](C)C>>[CH3:18][O:12][C:2]1[CH2:3][CH2:4][CH2:5][C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[N:1]=1

Participants

3

Reactant 2

HCID 2485801,3,4,5-Tetrahydro-2H-1-benzazepin-2-oneHCID 2735153Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1)

Product 1

HCID 18428530HCID 18428530, compound

Procedure

A sample of the title compound of EXAMPLE 165 (3.2 g, 20.0 mmol) was reacted with trimethyloxonium tetrafluoroborate (4.4 g, 30.0 mmol) by the method of EXAMPLE 26 to yield, after chromatography, 2.5 g (73%) of the title material.

Workup

  1. customto yield

Sources & evidence

ORD record
ord-fa5249ba61ce4fecb742ff29d4161583
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

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