Ammonium Chloride → HCID 178479030, compound

HRID 1459220Notes

Reaction equation

HRID 1459220 reaction equation
CO[C:3]1[CH2:9][CH2:8][CH2:7][C:6]2[CH:10]=[CH:11][CH:12]=[CH:13][C:5]=2[N:4]=1.[Cl-:14].[NH4+:15]>CO.C(Cl)Cl>[ClH:14].[NH:4]1[C:5]2[CH:13]=[CH:12][CH:11]=[CH:10][C:6]=2[CH2:7][CH2:8][CH2:9][C:3]1=[NH:15]

Participants

5

Reactant 2

HCID 25517Ammonium ChlorideHCID 18428530HCID 18428530, compound

Product 1

HCID 178479030HCID 178479030, compoundYield 91.3%

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6344DichloromethaneSolvent

Procedure

The product of EXAMPLE 166 (1.9 g, 11.1 mmol) in 15 mL of MeOH and 10 mL of CH2Cl2 was reacted with ammonium chloride (413 mg, 7.8 mmol) by the method of EXAMPLE 27 to yield 1.4 g (88%) of the title material.

Sources & evidence

ORD record
ord-0874f127bddd4fa9a2191116fab1ef13
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

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