Ammonium Chloride → HCID 178440873, compound

HRID 1459226Notes

Reaction equation

HRID 1459226 reaction equation
[CH2:1]([CH:5]1[CH2:11][CH2:10][CH2:9][CH2:8][C:7](OC)=[N:6]1)[CH2:2][CH2:3][CH3:4].[Cl-:14].[NH4+:15]>CO>[ClH:14].[CH2:1]([CH:5]1[NH:6][C:7](=[NH:15])[CH2:8][CH2:9][CH2:10][CH2:11]1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 10702611HCID 10702611, compound

Product 1

HCID 178440873HCID 178440873, compoundYield 90.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of EXAMPLE 186 (500 mg, 2.7 mmol) in 20 mL of MeOH was reacted with ammonium chloride (124 mg, 2.3 mmol) by the method of EXAMPLE 27 to yield 425 mg (74%) of the title material.

Sources & evidence

ORD record
ord-04b93dfccf0041d39b0a90cdde0b4b35
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

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