Ammonium Chloride → HCID 178442371, compound

HRID 1459229Notes

Reaction equation

HRID 1459229 reaction equation
[CH2:1]([CH:3]([CH2:14][CH3:15])[CH2:4][CH:5]1[CH2:11][CH2:10][CH2:9][CH2:8][C:7](OC)=[N:6]1)[CH3:2].[Cl-:16].[NH4+:17]>CO>[ClH:16].[CH2:1]([CH:3]([CH2:14][CH3:15])[CH2:4][CH:5]1[NH:6][C:7](=[NH:17])[CH2:8][CH2:9][CH2:10][CH2:11]1)[CH3:2]

Participants

4

Reactant 2

HCID 25517Ammonium ChlorideHCID 10750993HCID 10750993, compound

Product 1

HCID 178442371HCID 178442371, compoundYield 57.8%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product of EXAMPLE 196 (470 mg, 2.2 mmol) in 18 mL of MeOH was reacted with ammonium chloride (98 mg, 1.8 mmol) by the method of EXAMPLE 27 to yield 242 mg of the title material.

Sources & evidence

ORD record
ord-7690585fa8364c538f1cdb2a622e6b77
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

Loading…