N-ethyl-4-methylpyridin-2-amine → HCID 178476385, compound

HRID 1459271Notes

Reaction equation

HRID 1459271 reaction equation
[C:1]([OH:4])(=[O:3])[CH3:2].N=C1CC(C)CCN1.[CH2:13]([NH:15][C:16]1[CH:21]=[C:20]([CH3:22])[CH:19]=[CH:18][N:17]=1)[CH3:14]>>[C:1]([OH:4])(=[O:3])[CH3:2].[CH3:14][CH2:13][N:15]=[C:16]1[CH2:21][CH:20]([CH3:22])[CH2:19][CH2:18][NH:17]1

Participants

3

Reactant 2

HCID 18428456N-ethyl-4-methylpyridin-2-amineHCID 1784758702-Imino-4-methylpiperidine acetate

Product 1

HCID 178476385HCID 178476385, compound

Procedure

The method of preparation of 2-imino-4-methylpiperidine acetate was used to convert 2-(ethylamino)-4-methylpyridine to the title compound except platinum oxide was used as the catalyst. The analysis of the product, obtained as an oil, was found to be consistent with the proposed structure. MH+=141; 1H NMR (D2O): 3.40-3.10 (m, 2H); 3.00 (q, J=6 Hz, 2H); 2.50-2.40 (m, 1H); 2.10-1.90 (m, 1H); 1.83 (s, 3H); 1.80-1.65 (m, 4H); 1.40-1.20 (m 1H); 1.02 (t, J=6 Hz, 3H); 0.83 (d, J=6 Hz, 3H).

Sources & evidence

ORD record
ord-2362ace83b354d5bab0dcd2fe4c612ae
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

Loading…