Water → HCID 15278732, compound

Participants

Reaction Conditions

Reaction Steps

13.3 g of zinc powder are added in portions to a mixture of 12 g of N-tert-butyl-2-ethylmercapto-5-nitrobenzenesulfonamide, 17.7 g of ammonium chloride, 50 ml of water and 200 ml of ethanol and the mixture is stirred at 70° C. for 10 hours. After the solid has been filtered off and washed out with ethyl acetate, the filtrate is concentrated under reduced pressure. The residue from the filtrate is taken up in ethyl acetate and the mixture is washed with water. After drying over magnesium sulfate, the organic phase is concentrated. 9.4 g of the desired aniline are thus obtained;

Provenance & Evidence