HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dimethylbenzoyl chloride → N-[4-[(6,11-Dihydro-5H-dibenz[b,e]azepin-5-yl)-carbonyl]phenyl]-2,3-dimethylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dimethylbenzoyl chloride | HCID 2800899 | — |
| Reactant | 5-(4-Aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine | HCID 15410467 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-[4-[(6,11-Dihydro-5H-dibenz[b,e]azepin-5-yl)-carbonyl]phenyl]-2,3-dimethylbenzamide | HCID 67623756 | 13.4% |
Reaction Steps
As described for Example 9, 0.628 g (2 mmol) of 5-(4-aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine is reacted with 0.506 g (3.0 mmol) of 2,3-dimethylbenzoyl chloride in dichloromethane. The product is recrystallized from hexane-dichloromethane to give 0.12 g of crystals, m.p. 138°-142° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05854236 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-64c9a81efc954c66a134162f91594680 |
| Source note | uspto-grants-1998_12 |