HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1459451Generated: October 31, 2026
4-Methoxybenzylamine → HCID 54046710, compound
https://huagongshe.com/reaction/1459451
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methoxybenzylamine | HCID 75452 | — |
| Reactant | 2,5-Dichloropyridine-3-carboxylic acid | HCID 2736085 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 54046710 | HCID 54046710 | — |
Reaction Steps
A mixture of 2,5-dichloronicotinic acid (30.0 g) and 4-methoxybenzylamine (41.0 ml) was heated at 150° C. under nitrogen for 2 hours. The mixture was cooled to ambient temperature, dissolved in boiling water, acidified to pH 6 and filtered. The collected solid was dried, boiled up with IMS, then filtered to give 5-chloro-2-(4-methoxybenzylamino)nicotinic acid, m.p. 204°-206° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05854257 |
|---|
| Source dataset | uspto-grants-1998_12 |
|---|
| ORD ID | ord-c7f1f194e7ea4dc9abd197a90deb56e0 |
|---|
| Source note | uspto-grants-1998_12 |
|---|
