Water → 4-(2-Pyridyl)Benzoic Acid

HRID 1459631Notes

Reaction equation

HRID 1459631 reaction equation
[C:1]1([CH3:13])[CH:6]=[CH:5][C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][N:8]=2)=[CH:3][CH:2]=1.[Mn]([O-])(=O)(=O)=[O:15].[K+].[OH2:20]>>[N:8]1[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=1[C:4]1[CH:5]=[CH:6][C:1]([C:13]([OH:15])=[O:20])=[CH:2][CH:3]=1

Participants

4

Reactant 3

HCID 962WaterHCID 782192-(p-Tolyl)pyridineHCID 516875Potassium Permanganate

Product 1

HCID 8216924-(2-Pyridyl)Benzoic Acid

Procedure

A suspension of 2-(p-tolyl)pyridine (2.00 g, 11.8 mmol) and potassium permanganate (5.60 g, 35.5 mmol), in water (25 mL) was heated at reflux for 2 hours. The reaction was allowed to cool to ambient temperature and filtered through celite to remove the solids. Acetic acid (1 mL) was added to the colorless filtrate and the product was collected as a white solid by filtration.

Workup

  1. temperatureat reflux for 2 hours
  2. filtrationfiltered through celite
  3. customto remove the solids
  4. additionAcetic acid (1 mL) was added to the colorless filtrate
  5. filtrationthe product was collected as a white solid by filtration

Sources & evidence

ORD record
ord-446900a7854046069918be0d7cbca524
Source dataset
uspto-grants-1998_12
Patent number
US05854264

Reaction notes

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