4-N-Boc-4-N-Methyl-aminopiperidine → HCID 131721052, compound

HRID 1459705Notes

Reaction equation

HRID 1459705 reaction equation
[C:1]([O:5][C:6]([N:8]([CH:10]1[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]1)[CH3:9])=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:16][O:17][CH:18]([O:24][CH3:25])[CH2:19][CH2:20][CH2:21][CH2:22]Br>>[CH3:16][O:17][CH:18]([O:24][CH3:25])[CH2:19][CH2:20][CH2:21][CH2:22][N:13]1[CH2:12][CH2:11][CH:10]([N:8]([C:6]([O:5][C:1]([CH3:4])([CH3:2])[CH3:3])=[O:7])[CH3:9])[CH2:15][CH2:14]1

Participants

3

Reactant 2

HCID 27568064-N-Boc-4-N-Methyl-aminopiperidineHCID 110746845-bromo-1,1-dimethoxypentane

Product 1

HCID 131721052HCID 131721052, compound

Procedure

The title compound was prepared from the above amine and 5-bromopentanal dimethyl acetal using a similar method to that described for Example 8 (Step 2). δ (360 MHz, CDCl3) 1.34 (1H, m), 1.46-1.73 (19H, m and s), 1.98 (2H, m), 1.33 (2H, m), 2.73 (3H, s), 2.99 (2H, m), 3.31 (6H, s), 4.36 (1H, t).

Sources & evidence

ORD record
ord-459f5754eee0492f989e17eba5cbd9a0
Source dataset
uspto-grants-1998_12
Patent number
US05854268

Reaction notes

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