HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 9-Ethyl-7-methyl-4-(dimethylamino)-2-(methylthio)imidazo[5,1-h]pteridin-6(5H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 4,6-Dichloro-2-(methylthio)-5-nitropyrimidine | HCID 11345458 | — |
| Reactant | HCID 178437635 | HCID 178437635 | — |
| Product | 9-Ethyl-7-methyl-4-(dimethylamino)-2-(methylthio)imidazo[5,1-h]pteridin-6(5H)-one | HCID 19358871 | — |
Reaction Steps
Prepared by treatment of 4,6-dichloro-5-nitro-2-(methylthio)pyrimidine with dimethylamine, followed by reaction with 2-ethyl-4-methylimidazole, reduction with tin (II) chloride, and cyclization with carbonyldiimidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05854419 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-45dbb8113be94229b7d5849d6e249a09 |
| Source note | uspto-grants-1998_12 |