反应详情

4,698 g (0.03 mol) of 4-methoxybenzyl chloride and 10.22 g (0.09 mol) of 2-chloropyridine were reacted in 40 ml of methanol at 40° C. for 3 days. After the reaction, the solvent was evaporate in vacuo and ether-water was added to the residue to extract unreacted reactants in the etherial layer. To the aqueous layer containing the pyridinium chloride was added 7.764 g (0.03 mol) of sodium hexafluoroantimonate. The resulting crystals were suction filtered, washed and dried to give the title compound melting at 122°-124° C.

1. customAfter the reaction
2. customthe solvent was evaporate in vacuo and ether-water
3. additionwas added to the residue
4. extractionto extract unreacted reactants in the etherial layer
5. additionTo the aqueous layer containing the pyridinium chloride
6. filtrationfiltered
7. washwashed
8. customdried