HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenol → HCID 15045663, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenol | HCID 4684 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 1-Pentyne, 5-chloro- | HCID 84308 | — |
| Catalyst | Tetrabutylammonium Iodide | HCID 67553 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 15045663 | HCID 15045663 | — |
Reaction Steps
To a mixture of 51.4 g (0.4 mol) of 4-chlorophenol, 49.2 g (0.48 mol) of 5-chloro-1-pentyne and 7.36 g (20 mmol) of tetra-n-butyl ammonium iodide in 140 mL of ethanol is added a solution of 24.7 g (0.44 mol) of potassium hydroxide in 24 mL of water over 2 minutes. The mixture is heated to reflux and is maintained for 25 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05070207 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-d205203aef634d998f7ca37e4106c810 |
| Source note | uspto-grants-1991_12 |