HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 15019923, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Nitrobenzene | HCID 7416 | — |
| Reactant | Acryloyl chloride | HCID 13140 | — |
| Reactant | Phenol, 4-[(4-aminophenyl)sulfonyl]- | HCID 117686 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15019923 | HCID 15019923 | — |
Reaction Steps
A mixture of 4-(4'-hydroxyphenylsulfonyl)aniline (23.3 g), pyridine (9.4 g) and nitrobenzene (1 ml) is added to 400 ml of tetrahydrofuran. To the ice-cooled solution, 9.0 g of acrylic acid chloride is added dropwise and stirred for 30 min. The stirred mixture is added to 2,000 ml of water and the precipitating crystal is separated by filtration. The resulting crystal is recrystallized with ethanol to obtain the end compound in an amount of 28.5 g. The structure of this compound is verified by IR, NMR and mass spectra.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05071738 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-342b39efb741490ab8fb551f708e8e4e |
| Source note | uspto-grants-1991_12 |