HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-2-nitroanisole → 5-Fluoro-2-methoxyaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-2-nitroanisole | HCID 565656 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 5-Fluoro-2-methoxyaniline | HCID 223105 | 100.5% |
Reaction Steps
A solution of 20.5 g of 4-fluoro-2-nitroanisole in ethyl acetate was hydrogenated over 5% palladium carbon (2 g) at room temperature for 16 hours. The catalyst was removed by filtration and the filtrate evaporated to leave 17 g of the title compound as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05071863 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-e245d9a78ba942b289a188b1b19d29a9 |
| Source note | uspto-grants-1991_12 |