HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Chloro-1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 15070064, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Chloro-1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 9835941 | — |
| Reactant | 1-Methyloctahydropyrrolo[3,4-B]pyrrole | HCID 15070001 | — |
| Product | HCID 15070064 | HCID 15070064 | — |
Reaction Steps
Thus, for example, 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylicacid can be reacted with 2-methyl-2,7-diazabicyclo[3.3.0]octane to give 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(2-methyl-2,7-diazabicyclo[3.3.0]oct-7-yl)-4-oxo-3-quinolinecarboxylic acid, which has a high antibacterial activity.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05071999 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-573e2ad65ced469c9e5f1aca01cc3edf |
| Source note | uspto-grants-1991_12 |