反应详情

21.2 g (77.3 mmol) of ethyl 2-benzyl-2,7-diazabicyclo[3.3.0]octane-7-carboxylate in 400 ml of ethanol are hydrogenated at 100° C. and 100 bar on 3 g of palladium-active carbon (10% Pd). The catalyst is filtered off, the filtrate is concentrated and the residue is distilled.

1. customare hydrogenated at 100° C.
2. filtrationThe catalyst is filtered off
3. concentrationthe filtrate is concentrated
4. distillationthe residue is distilled