Formic Acid → HCID 19738527, compound

HRID 1460800Notes

Reaction equation

HRID 1460800 reaction equation
C[O:2][CH:3](OC)[CH2:4][N:5]([CH2:11][C:12]([F:14])=[CH2:13])[C:6](=[O:10])[O:7][CH2:8][CH3:9].C(O)=O.[Cl-].[Na+]>O>[F:14][C:12](=[CH2:13])[CH2:11][N:5]([CH2:4][CH:3]=[O:2])[C:6](=[O:10])[O:7][CH2:8][CH3:9]

Participants

5

Reactant 3

HCID 284Formic AcidHCID 5234Sodium ChlorideHCID 19738534HCID 19738534, compound

Product 1

HCID 19738527HCID 19738527, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

14.1 g (60 mmol) of ethyl N-(2,2-dimethoxyethyl) -N-(2-fluoroallyl)-carbamate are heated under reflux for three hours with 6.3 ml of formic acid in 120 ml of water. The solution is saturated with sodium chloride and extracted several with methylene chloride, the organic solutions are washed with saturated sodium hydrogen carbonate solution, dried over magnesium sulphate and concentrated, and the residue is distilled.

Workup

  1. extractionextracted several with methylene chloride
  2. washthe organic solutions are washed with saturated sodium hydrogen carbonate solution
  3. dry with materialdried over magnesium sulphate
  4. concentrationconcentrated
  5. distillationthe residue is distilled

Sources & evidence

ORD record
ord-db55e1700f37475e83e34a6e75a9cb74
Source dataset
uspto-grants-1991_12
Patent number
US05071999

Reaction notes

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