Carbon Dioxide → HCID 19100935, compound

HRID 1460801Notes

Reaction equation

HRID 1460801 reaction equation
[F:1][C:2](=[CH2:13])[CH2:3][N:4]([CH2:10][CH:11]=O)[C:5](=[O:9])[O:6][CH2:7][CH3:8].[CH2:14]([NH:21][CH2:22]C(O)=O)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.C(=O)=O>C1(C)C=CC=CC=1>[CH2:14]([N:21]1[CH2:22][CH2:13][C:2]2([F:1])[CH:11]1[CH2:10][N:4]([C:5]([O:6][CH2:7][CH3:8])=[O:9])[CH2:3]2)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

5

Reactant 3

HCID 280Carbon DioxideHCID 869652-(Benzylamino)acetic acidHCID 19738527HCID 19738527, compound

Product 1

HCID 19100935HCID 19100935, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

20.8 g (0.11 mol) of ethyl N-(2-fluoroallyl)-N -(2-oxoethyl)-carbamate are heated under reflux with 19 g (0.115 mol) of N-benzylglycine in 300 ml of toluene until evolution of CO2 is complete. The mixture is concentrated and the residue is distilled.

Workup

  1. concentrationThe mixture is concentrated
  2. distillationthe residue is distilled

Sources & evidence

ORD record
ord-0cd2644fd2864aefbc3c0f20d30d0854
Source dataset
uspto-grants-1991_12
Patent number
US05071999

Reaction notes

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