Water → HCID 19100950, compound

HRID 1460805Notes

Reaction equation

HRID 1460805 reaction equation
[CH2:1]=[CH:2][CH:3]([N:5]([CH2:11][CH:12]=O)[C:6](=[O:10])[O:7][CH2:8][CH3:9])[CH3:4].[CH2:14]([NH:21][CH2:22]C(O)=O)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.O>C1(C)C=CC=CC=1>[CH2:14]([N:21]1[CH2:22][CH2:1][CH:2]2[CH:12]1[CH2:11][N:5]([C:6]([O:7][CH2:8][CH3:9])=[O:10])[CH:3]2[CH3:4])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

5

Reactant 3

HCID 962WaterHCID 869652-(Benzylamino)acetic acidHCID 19738508HCID 19738508, compound

Product 1

HCID 19100950HCID 19100950, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

11.6 g (62.6 mmol) of ethyl N-(1-buten-3-yl)-N -(2-oxoethyl)-carbamate and 10.4 g (62.6 mmol) of N -benzylglycine in 170 ml of toluene are heated under reflux overnight in a water separator. The mixture is concentrated and the residue is distilled.

Workup

  1. concentrationThe mixture is concentrated
  2. distillationthe residue is distilled

Sources & evidence

ORD record
ord-6a8e30f268ae4917a1a99fba70acd916
Source dataset
uspto-grants-1991_12
Patent number
US05071999

Reaction notes

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