Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1460836Generated: October 25, 2026

4-methoxy-2,5-dihydro-1H-pyrrol-2-one → 6-cyano-3,4-dihydro-2,2-dimethyl-trans-3-hydroxy-4-(4-methoxy-2-oxo-3-pyrrolin-1-yl)-2H-1-benzopyran

https://huagongshe.com/reaction/1460836

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-methoxy-2,5-dihydro-1H-pyrrol-2-oneHCID 574769—
Reactant2,2-Dimethyl-3,4-epoxy-6-cyanochromanHCID 10867360—
Reactant4-Octyloxy-3-pyrrolin-2-oneHCID 19982578—
Product6-cyano-3,4-dihydro-2,2-dimethyl-trans-3-hydroxy-4-(4-methoxy-2-oxo-3-pyrrolin-1-yl)-2H-1-benzopyranHCID 67924112—

Reaction Steps

Similarly, optionally replacing 6-cyano-3,4-dihydro-2,2-dimethyl-3,4-epoxy-2H-1-benzopyran with the appropriate compound of formula (2), and optionally replacing 4-methoxy-3-pyrrolin-2-one with the appropriate compound of formula (3), the following compounds of formula (I) are prepared:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05072006
Source datasetuspto-grants-1991_12
ORD IDord-4baf28b8fccf4c068d254fa140172645
Source noteuspto-grants-1991_12