反应详情

34.6 g (0.27 mole) of 2,3-difluoropropanoyl chloride were added dropwise to a solution of 50 g (0.27 mole) of 2,2,3,4,4,4-hexafluoro-1-butanol and 21.6 g (0.27 mole) of pyridine in 200 ml of dry tetrachloromethane. Stirring was continued for a further 1 hour and then the mixture was poured into water, extracted, dried and distilled. In this manner, 56 g of 2,2,3,4,4,4-hexafluorobutyl 2,3-difluoropropionate were obtained having a melting point of 84° to 86° C. at 20 mbar. The purity of the product prepared was 95% (determined by gas chromatography).

1. extractionextracted
2. customdried
3. distillationdistilled