HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminophenol → 3-Hydroxyacetanilide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminophenol | HCID 11568 | — |
| Reactant | Acetic acid 10-acetoxymethyl-anthracen-9-ylmethyl ester | HCID 613145 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Hydroxyacetanilide | HCID 12124 | 92% |
Reaction Steps
Acetic anhhydride (21.2 ml, 220 mmol) was slowly added to a suspension of m-aminophenol (24.0 g, 220 mmol) in 60% of crushed ice and 60 ml of cold water. The reaction mixture was vigorously stirred for 30 minutes. The white precipitate was filtered, washed with cold water, and air-dried to give 30.5 g (92%) of pure 3-acetamidophenol, m.p. 147°-149° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05073173 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-e8fe6d4de04d4d80bb48f57764ff7fbc |
| Source note | uspto-grants-1991_12 |