Water → 4-chloro-N-hexadecyl-N-methyl-3-nitrobenzenesulfonamide

Participants

Reaction Steps

N-Hexadecyl-3-nitro-4-chlorobenzenesulfonamide (170 grams) was dissolved in 640 ml of acetone. 79 grams of potassium carbonate, 6 ml of polyethylene glycol and 71 grams of dimethylsulfate were added and the mixture was heated under reflux for a period of 5 hours. Acetone (240 ml) was then added and 870 ml of water was added dropwise at 40° C. and crystals precipitated out on cooling the mixture to room temperature. The crystals were recovered by filtration, washed with water and methanol and then dried.

Provenance & Evidence