Triethyloxonium tetrafluoroborate → HCID 21250834, compound

HRID 1460981Notes

Reaction equation

[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:11][CH2:12][CH2:13][CH3:14])=[C:6]([CH:10]=1)[C:7]([NH2:9])=[O:8].[F:15][B-:16]([F:19])([F:18])[F:17].[CH2:20]([O+](CC)CC)[CH3:21]>>[F:15][B-:16]([F:19])([F:18])[F:17].[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:11][CH2:12][CH2:13][CH3:14])=[C:6]([CH:10]=1)[C:7](=[NH:9])[O:8][CH2:20][CH3:21]

Participants

Reactant 2

HCID 2723982Triethyloxonium tetrafluoroborate

HCID 21250742HCID 21250742, compound

Product 1

HCID 21250834HCID 21250834, compound

Procedure

reaction of 5-fluoro-2-propoxybenzamide (16.40 g) with triethyloxonium tetrafluoroborate yielded ethyl 5-fluoro-2-propoxybenzimidate tetrafluoroborate which on reaction with a saturated solution of ethanolic ammonia yielded 5-fluoro-2-propoxybenzamidine (8.40 g);

Sources & evidence

ORD record: ord-5150565b4e344d40b3378355c90d2ff9
Source dataset: uspto-grants-1991_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05073559

Reaction notes

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