Thionyl Chloride → 6-(4-Chlorobenzoyl)-1-methyl-1H-benzotriazole

HRID 1461086Notes

Reaction equation

HRID 1461086 reaction equation
[CH3:1][N:2]1[C:6]2[CH:7]=[C:8]([C:11]([OH:13])=O)[CH:9]=[CH:10][C:5]=2[N:4]=[N:3]1.S(Cl)(Cl)=O.[Al+3].[Cl-:19].[Cl-].[Cl-]>ClC1C=CC=CC=1>[Cl:19][C:5]1[CH:10]=[CH:9][C:8]([C:11]([C:8]2[CH:9]=[CH:10][C:5]3[N:4]=[N:3][N:2]([CH3:1])[C:6]=3[CH:7]=2)=[O:13])=[CH:7][CH:6]=1

Participants

5

Reactant 3

HCID 24386Thionyl ChlorideHCID 6451240Aluminum(III) ChlorideHCID 178364261-methyl-1H-1,2,3-benzotriazole-6-carboxylic acid

Product 1

HCID 189243106-(4-Chlorobenzoyl)-1-methyl-1H-benzotriazole

Reagents, catalysts & solvents 1

HCID 7964ChlorobenzeneSolvent

Procedure

The carboxylic acid (b) is converted into the corresponding acid chloride with thionyl chloride and then reacted with chlorobenzene and AlCl3, yielding the title compound.

Sources & evidence

ORD record
ord-d6dce3c19bc246e39110cd356055f224
Source dataset
uspto-grants-1991_12
Patent number
US05073574

Reaction notes

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