Sodium borohydride → alpha-(4-chlorophenyl)-1-methyl-1H-benzotriazole-6-methanol
Reaction equation
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]([C:6]([C:8]2[CH:9]=[CH:10][C:11]3[N:15]=[N:14][N:13]([CH3:16])[C:12]=3[CH:17]=2)=[O:7])=[CH:4][CH:3]=1.[BH4-].[Na+]>>[Cl:1][C:2]1[CH:19]=[CH:18][C:5]([CH:6]([C:8]2[CH:9]=[CH:10][C:11]3[N:15]=[N:14][N:13]([CH3:16])[C:12]=3[CH:17]=2)[OH:7])=[CH:4][CH:3]=1Participants
3
Procedure
The keto compound (c) is reduced with sodium borohydride, yielding the title compound.
Sources & evidence
- ORD record
- ord-ac1755e9dafd4244be0771d8ec6bc9bd
- Source dataset
- uspto-grants-1991_12
- Patent number
- US05073574
Reaction notes
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