Methyl 6-dimethylamino-4,4-diphenyl-2-heptenoate → Methyl 6-dimethylamino-4,4-diphenyl-heptanoate

HRID 1461147Notes

Reaction equation

HRID 1461147 reaction equation
[CH3:1][N:2]([CH3:25])[CH:3]([CH3:24])[CH2:4][C:5]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH:6]=[CH:7][C:8]([O:10][CH3:11])=[O:9]>[Pd].CO>[CH3:25][N:2]([CH3:1])[CH:3]([CH3:24])[CH2:4][C:5]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)([C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)[CH2:6][CH2:7][C:8]([O:10][CH3:11])=[O:9]

Participants

4

Reactant 1

HCID 53841050Methyl 6-dimethylamino-4,4-diphenyl-2-heptenoate

Product 1

HCID 19981498Methyl 6-dimethylamino-4,4-diphenyl-heptanoate

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of methyl 6-dimethylamino-4,4-diphenyl-2-heptenoate (60 mg), 10% Pd/C (10 mg), and methanol was hydrogenated at room temperature for 18 hours. The mixture was filtered through a short pad of celite, and the filtrate was rotary evaporated to give methyl 6-dimethylamino-4,4-diphenyl-heptanoate, as a crude material which was then dried in vacuo.

Workup

  1. filtrationThe mixture was filtered through a short pad of celite
  2. customthe filtrate was rotary evaporated

Sources & evidence

ORD record
ord-d0420531e88d43e4ae9d467af14c0539
Source dataset
uspto-grants-1991_12
Patent number
US05073629

Reaction notes

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