Benzylamine → HCID 14793450, compound

Participants

Reaction Steps

482 mg (1.6 mM) of 2-cyano-2-methylhexyl p-acetoxybenzoate obtained in Step 1) was dissolved in 1.5 ml of dry ether, and a solution of 188 mg (1.6 mM) of benzylamine in 1 ml of ether was added thereto, followed by 24 hours of stirring at room temperature. After the reactions and distilling-off of the solvent, the product was purified by thin layer chromatography (developer solvent: ethyl acetate/methylene chloride=1:5) to obtain 339 mg of 2-cyano-2-methylhexyl p-hydroxybenzoate (yield 73.7%).

Provenance & Evidence