Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | 2-Furancarboxylic acid, 5-[(dimethylamino)methyl]-, ethyl ester | HCID 10035599 | — |
| Product | HCID 10104585 | HCID 10104585 | 104.6% |
Reaction Steps
A mixture consisting of 49.0 g (248 mmol) of ethyl 5-(dimethylaminomethyl)-2-furancarboxylate and 150 g (2.496 mol) of anhydrous ethylenediamine was heated at 80° C. for 2 hours. After cooling, the excess ethylenediamine was distilled off under reduced pressure to give 54.8 g (98.0%) of 5-(dimethylaminomethyl)-N-(2-aminoethyl)-2-furancarboxamide (Compound a) as light yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05075301 |
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| Source dataset | uspto-grants-1991_12 |
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| ORD ID | ord-e14d357ae5d74a0fabda7030b1bbb5c5 |
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| Source note | uspto-grants-1991_12 |
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