Ethylenediamine → HCID 10333205, compound

HRID 1461267Notes

Reaction equation

[CH:1]([N:4]([CH2:8][C:9]1[O:13][C:12]([C:14]([O:16]CC)=O)=[CH:11][CH:10]=1)[CH:5]([CH3:7])[CH3:6])([CH3:3])[CH3:2].[CH2:19]([NH2:22])[CH2:20][NH2:21]>>[CH:5]([N:4]([CH2:8][C:9]1[O:13][C:12]([C:14]([NH:21][CH2:20][CH2:19][NH2:22])=[O:16])=[CH:11][CH:10]=1)[CH:1]([CH3:2])[CH3:3])([CH3:6])[CH3:7]

Participants

Reactant 2

HCID 3301Ethylenediamine

HCID 10467449HCID 10467449, compound

Product 1

HCID 10333205HCID 10333205, compound

Procedure

Using Compound f and anhydrous ethylenediamine, the corresponding procedure of Example 1 was followed to give 5-(diisopropylaminomethyl)-N-(2-aminoethyl)-2-furancarboxamide as tan-colored oil. Reduction of this compound in the same manner as Example 1 without prior purification gave 5-(diisopropylaminomethyl)-N-(2-aminoethyl)furfurylamine (Compound g) as light yellow oil.

Sources & evidence

ORD record: ord-d9e89b96a9994085812cd5dbeba51afa
Source dataset: uspto-grants-1991_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05075301

Reaction notes

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