HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methyl-5,6-dihydroquinoline → 5,6,7,8-tetrahydro-7-(N-hydroxy-1-propylamino)-4-methylquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methyl-5,6-dihydroquinoline | HCID 12133620 | — |
| Reactant | N-propylhydroxylamine hydrochloride | HCID 12355438 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5,6,7,8-tetrahydro-7-(N-hydroxy-1-propylamino)-4-methylquinoline | HCID 14835950 | 73.4% |
Reaction Steps
This compound was prepared from the product of Step 6 (4.5 g, 30 mmol), 1-propylhydroxylamine hydrochloride (6 g, 55 mmol), and methanol (20 ml) by the method outlined in Example 10. The crude material was recrystallised from cyclohexane to give the product (4.85 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05075303 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-12d23821971b471a86277c7366c7d985 |
| Source note | uspto-grants-1991_12 |