反应详情

A stirred mixture of sulphuric acid (200 ml) and nitric acid (200 ml) was treated with 5,6,7,8-tetrahydroquinoline N-oxide (47 g, 315 mmol), heated at 60°-80 ° for 3h, cooled to room temperature, poured onto ice (1 Kg), diluted with water (1 1), and extracted with dichloromethane (3×500 ml). The extracts were dried (MgSO4) and evaporated in vacuo to give the product (48 g) as an oil.

1. additionpoured onto ice (1 Kg)
2. extractionextracted with dichloromethane (3×500 ml)
3. dry with materialThe extracts were dried (MgSO4)
4. customevaporated in vacuo