HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-propylhydroxylamine hydrochloride → 4-chloro-5,6,7,8-tetrahydro-7-(N-hydroxy-1-propylamino)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-propylhydroxylamine hydrochloride | HCID 12355438 | — |
| Reactant | 4-Chloro-5,6-dihydroquinoline | HCID 14835962 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-chloro-5,6,7,8-tetrahydro-7-(N-hydroxy-1-propylamino)quinoline | HCID 14835963 | 85.5% |
Reaction Steps
This compound was prepared from the product of Step 4 (4.35 g, 26 mmol), 1-propylhydroxylamine hydrochloride (6 g, 54 mmol), and methanol (10 ml) by the method described in Example 10. The residue was recrystallised from cyclohexane to give the product (5.35 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05075303 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-a2e0869b06bc4a549f3295387a1260af |
| Source note | uspto-grants-1991_12 |