HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Chloro-5,6,7,8-tetrahydro-7-(1-propylamino)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-chloro-5,6,7,8-tetrahydro-7-(N-hydroxy-1-propylamino)quinoline | HCID 14835963 | — |
| Catalyst | titanium(III) trichloride | HCID 10313229 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Chloro-5,6,7,8-tetrahydro-7-(1-propylamino)quinoline | HCID 14835964 | — |
Reaction Steps
This compound was prepared from the product of Step 5 (5.8 g, 24 mmol) titanium trichloride, 20 wt. % solution in 20 wt. % hydrochloric acid (28 ml, 36 mmol), and methanol (50 ml) using the procedure described in Example 11. The crude amine (5.4 g) was converted directly into the product of Step 7.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05075303 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-fad81e672b0e48eb8a316e3521d82cc9 |
| Source note | uspto-grants-1991_12 |