5,6-Dihydroquinoline → 5,6,7,8-Tetrahydro-7-dimethylaminoquinoline

HRID 1461293Notes

Reaction equation

[Cl-].[CH3:2][NH2+:3][CH3:4].[N:5]1[C:14]2[CH:13]=[CH:12][CH2:11][CH2:10][C:9]=2[CH:8]=[CH:7][CH:6]=1>>[CH3:2][N:3]([CH3:4])[CH:12]1[CH2:13][C:14]2[N:5]=[CH:6][CH:7]=[CH:8][C:9]=2[CH2:10][CH2:11]1

Participants

Reactant 2

HCID 123183175,6-Dihydroquinoline

HCID 12954980Dimethylazanium;chloride

Product 1

HCID 148359225,6,7,8-Tetrahydro-7-dimethylaminoquinoline

Procedure

This compound was prepared from dimethylammonium chloride (1.63 g, 20 mmol) and 5,6-dihydroquinoline (1.31 g, 10 mmol) using the experimental and purification method describes in Example 48. The product (0.72 g) was an oil which was identical to the compound isolated in Example 3.

Workup

custompurification method

Sources & evidence

ORD record: ord-8cf27b10e2d64258a70bc63b4b0d63ed
Source dataset: uspto-grants-1991_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05075303

Reaction notes

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