Dimethylformamide dimethyl acetal → Ethyl 2-(4-bromo-2,3,5,6-tetrafluorobenzoyl)-3-dimethylaminopropenoate

Participants

Reaction Steps

Dimethylformamide dimethylacetal (11.85 g) was added to a solution of 33.63 g ethyl 4-bromo-2,3,5,6-tetrafluorobenzoylacetate in 100 ml tetrahydrofuran cooled in an ice-bath. The reaction mixture was then immersed in a warm water bath in order to drive it to completion. The resulting solution was used directly in the next reaction.

Provenance & Evidence