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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 14614Generated: October 25, 2026

4-tert-Butylphenol → Rac-4-[2-(4-tertbutyl-phenoxy)-propionylamino]-thiophene-3-carboxylic acid

https://huagongshe.com/reaction/14614

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-tert-ButylphenolHCID 7393—
ReactantRac-4-(2-chloro-propionylamino)-thiophene-3-carboxylic acid methyl esterHCID 68688356—
ProductRac-4-[2-(4-tertbutyl-phenoxy)-propionylamino]-thiophene-3-carboxylic acidHCID 16068685—

Reaction Steps

In analogy to Example 2, the title compound was prepared using rac-4-(2-chloro-propionylamino)-thiophene-3-carboxylic acid methyl ester and 4-tert-butylphenol. MS (m/e): 346.2 (M−H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732452B2
Source datasetuspto-grants-2010_06
ORD IDord-b040bc29c3e64f11820358c03ca818b1
Source noteuspto-grants-2010_06