HuagongsheHuagongshe Chemistry Print Report · For research reference only
Meclofenamic Acid → Benzoic acid, 2-((2,6-dichloro-3-methylphenyl)amino)-, methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Meclofenamic Acid | HCID 4037 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Benzoic acid, 2-((2,6-dichloro-3-methylphenyl)amino)-, methyl ester | HCID 76743 | 89% |
Reaction Steps
2-[(2,6-Dichloro-3-methylphenyl)amino]benzoic acid is reacted with oxalyl chloride and methanol according to the procedure of Example 25 to give 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid, methyl ester in 89% yield; mp 132°-134° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05075330 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-34e22260154f4ef1a84678d6820e26bd |
| Source note | uspto-grants-1991_12 |