Epichlorohydrin → HCID 15035854, compound

Participants

Reaction Steps

N-(t-butyloxycarbonyl)-aminoethanethiol (40 g, 225 mmole) from Example 2, and epichlorohydrin (35.4 g, 383 mmole) in 300 mL of ethanol were cooled to 0° C. and treated with potassium carbonate (35.4 g). The reaction was warmed to room temperature over 90 minutes and filtered through celite. The volatiles were removed under reduced pressure to give a clear oil (62.09 g, 100% yield) D.C.I.M.S. 270(M+H).

Provenance & Evidence