HRID1461553

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID23994

Zinc

结构：CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN.CS(=O)(=O)O

HCID62881

Deferoxamine mesylate

C26H52N6O11S

PRODUCTS

生成物

结构：CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN.CS(=O)(=O)O.[Zn]

HCID86745316

未命名化合物

PROCEDURE

实验过程

10 mM solution of Desferal (Ciba Geigy, Basle) is mixed with an equal volume of 6 mM of ZnCL2 (A. R. Aldrich Chemical Co., Inc.) solution, titrated to pH 7.4. The mixture is heated for 30 min. to 45° C., and cooled and the complex Zn/Desferrioxamine B is formed. The ratio Zn:Desferal is 0.6:1.0.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-26ed8f68c8c344b199b77cc72c0f3eac
来源数据集: uspto-grants-1991_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05075469
来源说明: uspto-grants-1991_12

反应 SMILES

[Zn:1].[CH3:2][C:3]([N:5]([OH:40])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][NH:11][C:12]([CH2:14][CH2:15][C:16]([N:18]([OH:39])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][NH:24][C:25]([CH2:27][CH2:28][C:29]([N:31]([OH:38])[CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][NH2:37])=[O:30])=[O:26])=[O:17])=[O:13])=[O:4].[CH3:41][S:42]([OH:45])(=[O:44])=[O:43]>>[Zn:1].[CH3:2][C:3]([N:5]([OH:40])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][NH:11][C:12]([CH2:14][CH2:15][C:16]([N:18]([OH:39])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][NH:24][C:25]([CH2:27][CH2:28][C:29]([N:31]([OH:38])[CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][NH2:37])=[O:30])=[O:26])=[O:17])=[O:13])=[O:4].[CH3:41][S:42]([OH:45])(=[O:44])=[O:43]